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Prognostic Value of Residual Hypoventilation in Mechanically Ventilated Neuromuscular Patients (TcCO2-VAD)

C

Centre d'Investigation Clinique et Technologique 805

Status

Completed

Conditions

Home Mechanical Ventilation
Neuromuscular Disease

Treatments

Device: Capno-oxymetry monitoring

Study type

Observational

Funder types

Other

Identifiers

NCT02551406
TcCO2-VAD

Details and patient eligibility

About

Different tools may be used to monitor the efficacy of home mechanical ventilation. Investigators aimed to compare the prognostic value of the different data obtained by capno-oxymetry in a mechanical ventilated neuromuscular disease's population.

Full description

Home mechanical ventilation (HMV) is used to treat hypoventilation, and its efficacy is mostly assessed by daytime blood gases and nocturnal oxymetry (SpO2). Transcutaneous CO2 measure (TcCO2) has shown higher sensitivity than SpO2 to detect hypoventilation in neuromuscular diseases (NMD) patients. No data exist on the prognostic value of these techniques to monitor mechanical ventilated NMD patients.

Basing on retrospective data review, investigators aimed to compare the prognostic value of the data obtained using different tools to assess residual hypoventilation in the cohort of ventilated NMD patients followed at our reference center.

Enrollment

55 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • neuromuscular disease
  • age ≥18 years
  • mechanically ventilated
  • capno-oxymetry performed between 2009 and 2011

Exclusion criteria

  • Long-term oxygen therapy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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