Prognostic Value of Respiratory System Compliance Under VV-ECMO on 180-day Mortality in COVID-19 ARDS. (COMPLIECMO)

Central Hospital, Nancy, France

Status: Completed

Conditions: Mechanical Ventilation Pressure High; Ards; Extracorporeal Membrane Oxygenation

Treatments: Other: No applicable

Study type: Observational

Funder types: Other

Identifiers

NCT05341687

2022PI050

Details and patient eligibility

About

Mortality of patients with COVID-19 associated acute respiratory distress syndrome (CARDS) treated with veno-venous extra-corporal membrane oxygenation (vv-ECMO) is increasing over time since the beginning of the COVID-19 pandemic. The objectives were to retrospectively describe over the first ten days after vv-ECMO implantation, the ventilatory management of CARDS and to assess the impact of static respiratory system compliance (CRS) on the first day of vv-ECMO on 180-day mortality.

Enrollment: 122 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with ARDS secondary to COVID-19 pneumonia requiring ECMO-VV support, hospitalized in the intensive care units of the CHRU of Nancy, Marseille or Bordeaux between 01/03/2020 and 31/12/2021.
• Age > 18 years old

Exclusion criteria

• Respiratory parameters not available on ten first day of VV ECMO implantation.
• Patient refusal to participate in the study