Prognostic Value Related to the Presence of Thrombosis or Portal Vein Invasion in Patients With Hepatocellular Carcinoma Submitted to Surgery (HSL2012-06)

Hospital Sirio-Libanes

Status: Terminated

Conditions: Hepatic Portal Vein Tumor Invasion; Hepatocellular Carcinoma; Portal Vein Thrombosis

Study type: Observational

Funder types: Other

Identifiers

NCT01690715

HSL 2012/06

Details and patient eligibility

About

A retrospective study based on analysis of medical records of patients with hepatocellular carcinoma treated at the Hospital Sírio-Libanês (Sao Paulo-Brazil) between 2001 and 2011 with diagnosis confirmed by imaging or histological specimen underwent surgical resection with curative intent. The study aims to determine the prognostic value of vascular complications related to cancer and to evaluate the survival rate of these patients, comparing the data with those reported in the literature.

Enrollment: 50 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• hepatocellular carcinoma confirmed by imaging or histological specimen underwent surgical resection, with or without hepatic cirrhosis association;
• presence of venous outflow obstruction, either by direct tumor invasion or thrombosis, on portal vein or one of its main vessels;

Exclusion criteria

• Patients undergoing prior systemic treatment;
• Patients presenting incomplete data that do not allow their classification according to the stratification models;
• Patients whose information of progression or death can not be recovered;

Trial design

50 participants in 1 patient group

Hepatocellular carcinoma underwent surgery