Programmes de Marche Active et qualité de Vie Dans la Maladie de Parkinson (ACTI-PARK)

Grenoble Alpes University Hospital Center (CHU)

Status: Withdrawn

Conditions: Parkinson Disease

Treatments: Behavioral: Physical training

Study type: Interventional

Funder types: Other

Identifiers

NCT05685095

38RC22.0105_ACTI-PARK

2022-A00678-35 (Other Identifier)

Details and patient eligibility

About

The aim of this randomized controlled pilot trial is to assess the impact of different gait rehabilitation programs on the level of physical activity and gait in daily life in patients with Parkinson's disease (PD).

Two groups of 25 patients with PD will benefit from one of two gait training programs (treadmill vs. nordic walking), 3 times a week for 12 weeks. Activity level and number of steps will be remotely recorded over 7 days before, at the end, 3 and 6 months after the end of the program. Quality of life will be recorded at each time point.

The impact of the gait programs on the patients' level of daily activity will be examined, comparing the changes brought about by the two programs, taking into account the modulating influence of age and cognitive function.

Gait under conditions of daily life will be compared to gait parameters collected in the laboratory.

Sex: All

Ages: 30+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parkinson's disease, diagnosed for at least 2 years,
• Medical treatment (if any) unchanged in the past 4 weeks at least
• Hoehn & Yahr score < 3
• Montreal cognitive assessment (MOCA) score between 20 and 30
• Able to understand the aim and methods of the study and provide signed informed consent-

Exclusion criteria

• Atypical parkinsonian syndrome
• Cardiovascular pathology preventing moderate physical exercise
• Orthostatic hypotension
• Any condition (other than PD) interfering with gait
• pregnant or nursing

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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0 participants in 2 patient groups

Treadmill walking

Experimental group

Description:

The training program will last 12 weeks and consist of treadmill walking. The duration of the walking bouts (and pauses), and the speed of the belt will be adjusted as needed following the patients' progress. Music will be added as suited to boost motivation and support regular cadence. All training sessions will be supervised.

Treatment:

Behavioral: Physical training

Nordic walking

Experimental group

Description:

The training program will last 12 weeks and consist of Nordic walking, taught and supervised by an adapted physical activity teacher. The session will be carried out outside, weather permitting. When possible, training will gather 2 to 4 patients for group emulation. The duration of the walking bouts (and pauses) will be adjusted to follow the patients' progress.

Treatment:

Behavioral: Physical training