Progranulin and CTRP3 in Metabolic Syndrome

Korea University

Status: Completed

Conditions: Metabolic Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT01668888

KoreaHealth_Progranulin

Details and patient eligibility

About

Inflammation has been known to be a pivotal pathogenic mechanism of obesity-related disorders such as type 2 diabetes, metabolic syndrome and atherosclerosis. Adipose tissue functions as a major endocrine organ by adipokine mediated modulation of a number of signaling cascades in target tissues, that has pro-inflammatory or anti-inflammatory activities. Progranulin and CTRP3 are recently discovered novel adipokines. Therefore, the investigators tried to clarify the clinical meaning of these two adipokines in the subjects with or without metabolic syndrome

Enrollment: 127 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 20<age<80
• apparently healthy subjects

Exclusion criteria

• a history of CVD
• diabetes
• stage 2 hypertension
• malignancy
• severe renal or hepatic disease

Trial design

127 participants in 1 patient group

Apparently Helathy Subjects