Progressive Resistance Exercise in Rheumatoid Arthritis

Federal University of São Paulo

Status and phase: Completed; Phase 4

Conditions: Rheumatoid Arthritis

Treatments: Other: Control group; Other: Experimental group

Study type: Interventional

Funder types: Other

Identifiers

NCT02219022

CEP/UNIFESP 1826/10

Details and patient eligibility

About

A randomized controlled trial with rheumatoid arthritis patients will be realized. Patients will be randomized into two groups. Experimental group will do a 12 weeks training of progressive resistance exercise for global muscles and remain with the clinical treatment and the control only remain with the clinical treatment. Patients will be evaluated at baseline, after 6, 12 and 24 weeks.

Enrollment: 60 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Rheumatoid arthritis according to American College of Rheumatology 2010
• Both genders
• Age between 18 and 65 years
• Functional class I, II and III
• Stable medication within the three months preceding the study
• Haven't done any kind of regular exercise (two or more times per Week) for at least three months before study start
• Have agreed to participate in the study and signed an informed consent form.

Exclusion criteria

• Participating in another type of study
• Have difficulty understanding the evaluation tools with fibromyalgia
• Joint deformities that make impossible do the exercises
• Other musculoskeletal diseases
• Other diseases that contraindicate exercises.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Control group

Active Comparator group

Description:

Patient remain with their usual clinical treatment.

Treatment:

Other: Control group

Experimental group

Experimental group

Description:

Patients in experimental group participated in a 12-week progressive resistance training using a maximum repetition exercise in which patients performed 1 Maximum Repetition with the maximum bearable weight. Once the 1 Maximum Repetitionwas determined, training was divided into the following regimen: 2 series of 8 repetitions, the first with 50% and the second with 70% of 1 Maximum Repetition. The exercises were knee extension and flexion and hip abduction and adduction, elbow extension and flexion, wrist extension and flexion and shoulder abduction and adduction and spine extension and flexion all performed in machines. The 1 Maximum Repetition load was reevaluated every 6 weeks. Patient remain with their usual clinical treatment.

Treatment:

Other: Experimental group

Other: Control group