Progressive Resistance Training Versus Relaxation for Breast Cancer Patients During Chemotherapy: Biological Mechanisms and Effects on Fatigue and Quality of Life (BEATE)

German Cancer Research Center

Status: Completed

Conditions: Breast Cancer; Cancer-related Fatigue

Treatments: Other: Supervised progressive muscle relaxation training (Jacobsen method); Other: Supervised progressive resistance training

Study type: Interventional

Funder types: Other

Identifiers

NCT01106820

BEATE-1

Details and patient eligibility

About

The purpose of this randomized intervention study is to investigate the effects and biological mechanisms of a supervised 12-week progressive resistance training on fatigue and quality of life in breast cancer patients during chemotherapy. To determine the effect of the exercise itself beyond potential psychosocial effects due to attention by trainers or the group support, patients in the control group have a comparable training schedule (i.e. 60 min, twice a week, for 12 weeks) but with relaxation training (Jacobsen method).

Enrollment: 101 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• breast cancer patient after lumpectomy or mastectomy, stage I-III
• adjuvant chemotherapy
• BMI at least 18

Exclusion criteria

• contraindication for exercise
• radiotherapy during intervention period

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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101 participants in 2 patient groups

Resistance training

Active Comparator group

Treatment:

Other: Supervised progressive resistance training

Relaxation training

Active Comparator group

Treatment:

Other: Supervised progressive muscle relaxation training (Jacobsen method)