Project RESIST: Increasing Resistance to Tobacco Marketing Among Young Adult Sexual Minority Women Using Inoculation Message Approaches

Abramson Cancer Center at Penn Medicine

Status: Completed

Conditions: Cigarette Smoking Behavior

Treatments: Other: Culturally tailored anti-smoking messages; Other: Non-culturally tailored interventions

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04812795

R01CA237670 (U.S. NIH Grant/Contract)

843579

Details and patient eligibility

About

Project RESIST is an R01 study funded by NCI focused on determining the effects of using culturally tailored inoculation approaches to increase resilience to tobacco marketing influences among young adult sexual minority women ages 18-30 and incorporates critical stakeholder inputs that support later adoption and implementation. The study team is utilizing formative research to design and pre-test anti-smoking messages and two national longitudinal online survey experiments.

Full description

This study will recruit 2000 young adult sexual minority women (SMW), ages 18-30 years, current smokers (n = 1000) and not current smokers (n=1000). The study team will randomly assign participants to a condition in which they will be exposed to either culturally tailored anti-smoking messages or non-tailored. Participants will receive these messages at baseline and 1, 2, and 3 weeks post baseline. They will be asked to complete a follow-up survey one month post baseline. Intentions to quit smoking as well as intention (among current smokers) and intention to purchase cigarettes (among current nonsmokers) will be measured at baseline and one-month post baseline.

Enrollment: 2,214 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ages 18-30
• Woman
• Identifies as a sexual minority (any sexual orientation other than heterosexual)
• Lives in the United States
• Able to take surveys in English

Exclusion criteria

• Under 18 or older than 30
• Men
• Heterosexual
• Lives outside the United States
• Unable to take survey in English

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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2,214 participants in 4 patient groups

Culturally tailored (Non-smokers)

Experimental group

Description:

The anti-smoking and anti-industry messages will be culturally tailored to specifically reach out to young adult SMW. They will receive only messages that are culturally tailored at baseline and weeks 1, 2, and 3. Culturally tailored anti-smoking messages: Anti-smoking messages that are culturally tailored for sexual minority women.

Treatment:

Other: Culturally tailored anti-smoking messages

Non-culturally tailored (Non-smokers)

Active Comparator group

Description:

The anti-smoking and anti-industry messages will not be culturally tailored. They will receive only messages that are not culturally tailored at baseline and weeks 1, 2 and 3. Non-culturally tailored interventions: Anti-smoking messages that are not culturally tailored for sexual minority women.

Treatment:

Other: Non-culturally tailored interventions

Culturally Tailored (Smokers)

Experimental group

Description:

The anti-smoking and anti-industry messages will be culturally tailored to specifically reach out to young adult SMW. They will receive only messages that are culturally tailored at baseline and weeks 1, 2, and 3. Culturally tailored anti-smoking messages: Anti-smoking messages that are culturally tailored for sexual minority women.

Treatment:

Other: Culturally tailored anti-smoking messages

Non-culturally Tailored (Smokers)

Active Comparator group

Description:

The anti-smoking and anti-industry messages will not be culturally tailored. They will receive only messages that are not culturally tailored at baseline and weeks 1, 2 and 3. Non-culturally tailored interventions: Anti-smoking messages that are not culturally tailored for sexual minority women.

Treatment:

Other: Non-culturally tailored interventions