Project to Improve the Diagnosis and Treatment Ability of Adult Severe Community Acquired Lower Respiratory Tract Infection

Peking University

Status: Completed

Conditions: CAP; COPD Exacerbation

Study type: Observational

Funder types: Other

Identifiers

NCT04959955

LM2016057

Details and patient eligibility

About

1. Objective to understand the proportion of atypical pathogens in the pathogens of SCAP and AECOPD in urban hospitals in China.
2. Objective to investigate the antimicrobial resistance of atypical pathogens in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and SCAP in urban hospitals.
3. Objective to master the important clinical characteristics of patients with acute exacerbation of SCAP and COPD caused by atypical pathogens and mixed infection in urban hospitals in China, and to put forward the experience judgment index.
4. Objective to evaluate the advantages of various diagnostic methods for atypical pathogens causing lower respiratory tract infection.
5. It is suggested that the current empirical treatment of SCAP and severe COPD in China should be improved.

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• SCAP
• AECOPD

Exclusion criteria

• Pregnant or lactating women.

  • Patients with bronchiectasis.

    • Patients with active pulmonary tuberculosis.

      • Aspiration pneumonia or obstructive pneumonia.

        • Two weeks before the onset of hospital treatment history, this infection can not be excluded from hospital acquired infection.

          • HIV positive patients (but HIV testing is not required).

            • Patients who are unable and / or unable to understand and / or implement the investigation protocol.

Trial design

200 participants in 2 patient groups

AECOPD group

CAP group