Prolactin Hormone in Oral Lichen Planus

October University for Modern Sciences and Arts

Status: Completed

Conditions: Oral Lichen Planus

Study type: Observational

Funder types: Other

Identifiers

NCT04785703

REC18-048

Details and patient eligibility

About

Oral lichen planus (OLP) is one of the most common mucosal diseases with autoimmune etio-pathogenesis with involvement of various cytokines similar to psoriasis.It generally occurs more commonly in females, in a ratio of 3:2. prolactin (PRL),It is a peptide hormone that has a role in autoimmune related diseases like systemic lupus erythematosus and , rheumatoid Artheritis. The role of PrL in OLP pathogenesis was never investigated.the aim of this study is to investigate the expression of PRL receptors in tissue biopsies of OLP patients.

Enrollment: 40 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with oral lichen planus
• systemically healthy

Exclusion criteria

• oral lichenoid lesions

Trial design

40 participants in 1 patient group

oral lichen planus group

Description:

patients with chronic bollus erosive lichen planus