Prolonged Cardiopulmonary Bypass Time as Predictive Factor for in Hospital Infection

University Hospital Basel

Status: Completed

Conditions: Bloodstream Infection (BSI)

Study type: Observational

Funder types: Other

Identifiers

NCT04548167

2020-00210 ch20Berdajs2;

Details and patient eligibility

About

This study is to analyse the demographics and microbiological factors concerning patients undergoing cardio surgical intervention using CPB complicated with bloodstream infection (BSI) postoperatively.

Full description

Infectious complications after cardiovascular surgery, especially in operations that use cardiopulmonary bypass (CPB), is associated with significant morbidity and increase in peri-operative mortality. Prolonged CPB usage could be predictive for early bloodstream infection following cardia surgery. This study is to analyse the demographics and microbiological factors concerning patients undergoing cardio surgical intervention using CPB complicated with bloodstream infection (BSI) postoperatively.

Enrollment: 7,064 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients undergoing cardiac surgery

Exclusion criteria

• patients having active or previous endocarditis
• patients whose causative microorganism of postoperative BSI was identical to that isolated from preoperative or intraoperative samples
• patients with common skin colonized microorganisms, such as coagulase-negative Staphylococci, Viridans group Streptococci, Corynebacterium species, Bacillus species, Propionibacterium species, and Aerococcus species or Micrococcus species, which were isolated from only a single blood sample and without evidence of clinical sepsis, because contamination was considered.