Prolonged Sitting on Responses to Short-Term Exercise Training

The University of Texas System (UT)

Status: Completed

Conditions: Atherosclerosis; Metabolic Syndrome

Treatments: Behavioral: Prolonged sitting with exercise; Behavioral: Active walking with exercise.

Study type: Interventional

Funder types: Other

Identifiers

NCT03352063

2017-07-0074

Details and patient eligibility

About

Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.

Enrollment: 12 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 to 35 years

Exclusion criteria

• cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
• respiratory problems
• musculoskeletal problems that prevent prolonged sitting or exercise
• obesity
• susceptibility to fainting
• pregnancy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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12 participants in 2 patient groups

Sitting with Exercise

Active Comparator group

Description:

Subjects will complete a short term training protocol while sitting \>11 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training.

Treatment:

Behavioral: Prolonged sitting with exercise

Walking with exercise

Active Comparator group

Description:

Subjects will complete a short term training protocol while sitting \<5 hours per day. This training will be preceded by a VO2max test to aid in setting the correct intensity for training. Subjects will be asked to complete three high fat tolerance tests. One to establish a baseline, the second to determine the acute effects of training, and a third at the completion of training to determine the cumulative effect of exercise training.

Treatment:

Behavioral: Active walking with exercise.