Promoting Adherence to Treatment for Latent TB Infection Through Text Messaging (TXT4MED)

University of Arizona

Status: Completed

Conditions: Latent Tuberculosis

Treatments: Behavioral: Regularly scheduled LTBI medication reminder text messages

Study type: Interventional

Funder types: Other

Identifiers

NCT02690818

TXT4MED

Details and patient eligibility

About

The purpose of this pilot study is to determine whether regularly scheduled medication reminder text messages (SMS) are effective in increasing latent tuberculosis infection (LTBI) treatment completion.

Full description

We aim to determine the feasibility and acceptability of text reminders for improving adherence in latent TB patients. Specific objectives of the current study are to: 1) Assess the feasibility of the intervention as indicated by participant recruitment and retention and; 2) Evaluate the acceptability of the intervention, as indicated by intervention adherence, outcome measurement rates, and feedback from participants.

Data will be used to design a definitive trial which will test the hypothesis that the intervention will improve medication adherence, as measured through an increase in treatment completion rates, and result in higher self-reported medication adherence, fewer missed appointments and doses, and a shorter course of treatment.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Consent to the study
• Own a mobile phone which operates on a telecom provider supported by our SMS platform
• Initiating or actively receiving treatment for LTBI at the Pima County TB Clinic in Tucson, AZ
• Prescribed self-administered therapy
• Report not having prior or current active TB disease
• Know how to and are able to receive SMS messages
• At least 18 years of age

Exclusion criteria

• Do not meet inclusion criteria
• Do not consent to study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Behavioral intervention arm

Experimental group

Description:

Regularly scheduled medication reminder text messages Daily LTBI text messages without the option to text back. The messages will read, "This is a reminder to take your medication." Standard of care: Monthly reminder call and clinic visit

Treatment:

Behavioral: Regularly scheduled LTBI medication reminder text messages

Control group receiving standard care

No Intervention group

Description:

Standard of care: Monthly reminder call and clinic visit