Promoting Antiretroviral Therapy Among Serodiscordant Couples to Reduce HIV Transmission

National Center for AIDS/STD Control and Prevention, China CDC

Status: Completed

Conditions: HIV

Treatments: Behavioral: comprehensive intervention components

Study type: Interventional

Funder types: Other

Identifiers

NCT01764282

2012ZX10001007-001

Details and patient eligibility

About

The purpose of this study is to evaluate the effectiveness of reducing HIV transmission among sero-discordant couples by applying comprehensive intervention components.

Full description

A cluster-randomized controlled trial was carried out in forty counties from 16 cities. The strategy of Social Marketing was applied to influence sero-discordant couples' behavioral changes including safer sexual intercourses, regular HIV testing for the negative partners, antiretroviral therapy initiation.

Enrollment: 11,096 patients

Sex: All

Ages: 18 to 59 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Couples are required to have a stable relationship and live together in the last 3 months;
• Older than 18 years and younger than 60 years; without regard to CD4 count;
• Open cohort(any newly diagnosed serodiscordant couples who are eligible for treatment will be included during the study period).

Exclusion criteria

• Couples are not have a stable relationship or do not live together in the last 3 months;
• Younger than 18 years old.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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11,096 participants in 2 patient groups

Intervention

Experimental group

Description:

comprehensive intervention components

Treatment:

Behavioral: comprehensive intervention components

Usual

No Intervention group

Description:

According the National HIV Antiretroviral treatment Guideline, provide treatment referrals for those treatment-eligible HIV-positive patients.