Promoting Long-term Behavior Change to Reduce CVD Risk

Stanford University

Status: Completed

Conditions: Obesity

Treatments: Behavioral: Behavioral lifestyle/weight-loss intervention

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00227006

R29HL060154 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Once intervention class or staff contact is removed, obese adults participating in behavioral weight-loss programs often give up healthy eating habits and regain weight. We examined whether taste-based goal setting, which minimizes perceived deprivation by promoting taste and moderation, would sustain long-term reductions in saturated fat and body mass index (BMI).

Full description

Once intervention class or staff contact is removed, obese adults participating in behavioral weight-loss programs often give up healthy eating habits and regain weight. We examined whether taste-based goal setting, which minimizes perceived deprivation by promoting taste and moderation, would sustain long-term reductions in saturated fat and body mass index (BMI). Participants were randomized to Taste-Based Choices (taste-based goal setting + a standard 6-month behavioral weight-loss intervention), Smart Consumers (a standard 6-month intervention alone) or Community Access (access to commercial/community-based behavioral weight-loss programs) and followed over 18 months. To test our hypotheses, we examined a set of orthogonal contrasts (TBC and SC vs. CA; TBC vs. SC) on reductions in saturated fat (Block FFQ) and clinic-measured BMI.

Enrollment: 163 patients

Sex: All

Ages: 25+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:- Body mass index between 27-37

• Physically inactive
• Able to participate in physical activity
• Percentage of daily calories from total fat 30% or more
• Free of diagnosed heart disease
• Stable on medications for 3 months or more Exclusion Criteria:- Diabetic
• Dysphoric (Beck Depression Inventory score greater than 18)
• Binge eating or bulimic (Eating Disorder Diagnostic Scale)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind

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163 participants in 3 patient groups

Taste-Based Goal Setting

Experimental group

Description:

6-month intervention (14 lifestyle counseling classes)

Treatment:

Behavioral: Behavioral lifestyle/weight-loss intervention

Smart Consumers

Active Comparator group

Description:

6-month intervention (14 lifestyle counseling classes)

Treatment:

Behavioral: Behavioral lifestyle/weight-loss intervention

Community Access

Active Comparator group

Description:

Can enroll in behavioral treatment programs available in the community that do not include medication or very-low calorie diets

Treatment:

Behavioral: Behavioral lifestyle/weight-loss intervention