Prone Breast Radiotherapy Treatment Planning Observational Study (HUGProne)

Vincent Vinh-Hung

Status: Active, not recruiting

Conditions: Breast Cancer Female

Treatments: Radiation: Prone and supine simulation

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT02237469

HUG 13-184R

Details and patient eligibility

About

The study purpose is to evaluate whether or not clinical characteristics of women with breast cancer can predict which position for radiation treatment, prone or supine, will be associated with a dosimetry gain. Dosimetry gain in this study means the lowest radiation dose to non-target organs (heart, lungs, contralateral breast), while giving the prescribed dose to tumor bed and ipsilateral breast.

Full description

Retrospectively identify women who received curative radiation treatment after breast conserving cancer surgery, in whom simulation in prone and in supine position was performed. Compare the treatment plans for doses to targets and to non-target organs, according to clinical parameters of body mass index, size of breast, location of tumor and side. Furthermore, evaluate whether a single CT slide is enough or not to predict a dosimetry advantage.

Enrollment: 280 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Breast conserving surgery
• Adjuvant radiation treatment
• Simulation done prone and supine

Exclusion criteria

• Simulation in only one position

Trial design

280 participants in 1 patient group

Prone and supine simulation

Description:

Women with breast cancer receiving simulation in prone and in supine position for adjuvant radiation treatment.

Treatment:

Radiation: Prone and supine simulation