Prone Breath Hold Technique to Decrease Cardiac and Pulmonary Doses in Women Receiving Left Breast Radiotherapy

University of Arizona

Status: Completed

Conditions: Breast Cancer

Treatments: Radiation: Verify radiation dose to heart and lung

Study type: Interventional

Funder types: Other

Identifiers

NCT02379988

1409500149

Details and patient eligibility

About

This is a pilot study to determine whether the addition of inspiratory hold (breath holding) can decrease the radiation dose that the heart and lung receive for patients being treated for left sided breast cancer.

Full description

Subjects have a standard of care CT simulation, which includes an additional breath hold CT. Inspiratory gated breath-hold will be used. Two radiation plans will be generated: one for the CT scan performed free breathing, and one for the CT scan performed with inspiratory gated breath hold. The cardiac and lung doses will be determined. At the discretion of the treating physician, the plan with the lower cardiac and lung dose may be used to treat the patient.

Enrollment: 15 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of Dr. Gonzalez
• ≥18 years of age
• Node-negative left breast cancer
• Invasive or DCIS breast cancer
• Prior lumpectomy
• Deemed appropriate for treatment in the prone position by the treating physician
• Able to tolerate prone position and breath hold during CT simulation

Exclusion criteria

• <18 years of age
• Patients requiring treatment in supine position

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

15 participants in 1 patient group

Verify radiation dose to heart and lung

Experimental group

Description:

Subjects will undergo the standard of care CT simulation, which includes an additional breath hold CT. Inspiratory gated breath-hold will be used. Two radiation plans will be generated: one for the CT scan performed free breathing, and one for the CT scan performed with inspiratory gated breath hold. The cardiac and lung doses will be determined. At the discretion of the treating physician, the plan with the lower cardiac and lung dose may be used to treat the patient.

Treatment:

Radiation: Verify radiation dose to heart and lung