Prone Duration in COVID-19 ARDS (PRODUR-CARDS)

Istanbul University - Cerrahpasa

Status: Completed

Conditions: Acute Respiratory Distress Syndrome (ARDS); COVID - 19

Study type: Observational

Funder types: Other

Identifiers

NCT06765759

2023/789

Details and patient eligibility

About

The aim of this observational study is to learn the effects of prone position duration on patient outcomes in patients with severe acute respiratory distress syndrome (ARDS) due to Coronavirus Disease - 2019 (COVID-19). The main question it aims to answer is:

Does the length of prone position duration affect gas exchange in patients with severe ARDS and is there a difference between genders in this regard? The differences in gas exchange between those who have been in prone position for 16-24 hours and those who have been in prone position for 24-36 hours as part of severe ARDS treatment will be examined.

Enrollment: 79 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >18 years old
• hospitalized for more than 48 hours
• patients diagnosed with COVID-19
• intubated patients
• underwent prone positioning for longer than 16 hours starting from the first session

Exclusion criteria

• Pregnant females
• Patients under the age of 18
• Those who did not reach 16 hours duration of prone position for various reasons (unintentional extubation, ventilation problems, hemodynamic instability, cardiac arrest-prearrest)

Trial design

79 participants in 2 patient groups

Short Prone

Description:

The group of patients who remained in prone position for 16-24 hours

Long Prone

Description:

The group of patients who remained in prone position for 24-36 hours