Prone Fluid Responsiveness in Children

Seoul National University

Status: Enrolling

Conditions: Pediatric ALL

Treatments: Procedure: TVC

Study type: Interventional

Funder types: Other

Identifiers

NCT05449886

2204-171-1321

Details and patient eligibility

About

In pediatric patients in the prone position, the reliability of pulse pressure variation and stroke volume variation, and pleth variability index to predict fluid responsiveness have not previously been established. Perioperatively, in this setting, optimizing fluid management can be challenging, and fluid overload is associated with both intraoperative and postoperative complications. The investigator designed this study to assess the sensitivity and specificity of baseline PPV, SVV, and PVI the tidal volume (VT) challenge (VTC) and in predicting fluid responsiveness during elective neurosurgery.

Enrollment: 40 estimated patients

Sex: All

Ages: 1 month to 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• elective neurosurgery and requiring prone positioning

Exclusion criteria

• (1) chronic cardiac arrhythmia; (2) depressed left (<30% of ejection fraction) (3) patients with pulmonary disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

40 participants in 1 patient group

Tidal volume challenge

Experimental group

Treatment:

Procedure: TVC