Prone Positioning vs. Prone Positioning and NO Inhalation in COVID-19 ARDS.

Fudan University

Status: Enrolling

Conditions: Respiratory Distress Syndrome

Treatments: Drug: Nitric oxide; Behavioral: prone positioning

Study type: Observational

Funder types: Other

Identifiers

NCT05715788

ppv-vs-ppvno

Details and patient eligibility

About

The investigators aim to investigate the effects of prone positioning and prone positioning with NO inhalation for COVID-19 patients with ARDS.

Full description

The investigators aim to investigate the effects of prone positioning and prone positioning with NO inhalation for COVID-19 patients with ARDS. Patients with COVID-19-associated ARDS were ventilated in prone position with or without NO inhalation, the arterial blood gas (ABG) tests were performed at 16 hours after prone positioning.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients with COVID-19 associated ARDS

Exclusion criteria

• patients who have contraindication for prone positioning, including pregnant, post-abdomen surgery within a week; hypercapnic respiratory failure

Trial design

30 participants in 2 patient groups

patients ventilated in prone position

Description:

Patients ventilated in prone position

Treatment:

Behavioral: prone positioning

Patients ventilated in prone position with NO inhalation

Description:

Patients ventilated in prone position with NO inhalation

Treatment:

Behavioral: prone positioning

Drug: Nitric oxide