Pronostic Score of Morbidity to Determine Risk of Complications After Endoscopic Submucosal Dissection for Colorectal Lesions

Central Hospital, Nancy, France

Status: Completed

Conditions: Polyp of Colon

Treatments: Procedure: endoscopic submucosal dissection

Study type: Observational

Funder types: Other

Identifiers

NCT04647266

2019PI285

Details and patient eligibility

About

The mains complications in colo-rectal dissection are the pain, the delayed bleeding and the perforation and represent around 10%.

Currently, the procedure is realized during a hospitalization with not real recommendation about the time of this.

There is currently no score established for the colo-rectal endoscopic submucosal dissection.

• To develop clinical or mixed prognostic score after endoscopic subcostal dissection for colorectal lesions in Nancy's hospital.
• Allow to obtain an estimation of number of patients required for a larger study.

Enrollment: 168 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient suffering of lesion relevant of endoscopic submucosal dissection treatment:
• Lesions for which en bloc resection with snare EMR is difficult to apply i/LST-NG, particularly LST-NG (PD) ii/ Lesions showing a VI-type pit pattern iii/ Carcinoma with shallow T1 (SM) invasion Large depressed-type tumors iv/ Large protruded-type lesions suspected to be carcinoma
• Mucosal tumors with submucosal fibrosis
• Sporadic tumors in conditions of chronic inflammation such as ulcerative colitis
• Local residual or recurrent early carcinomas after endoscopic resection Local res Les lésions de plus
• Male or female patients aged ≥ 18 years old
• Patients able to fill in questionnaires written in French

Exclusion criteria

• Suspicion of deep submucosal cancer by analysis of macroscopic appearance (Paris O-III), vascular pattern and pit pattern (SANO IIIB, KUDO Vn)