Proof-of-concept Study of Blood Markers of Tumor Dissemination in Patients with Versus Without Intestinal Polyps (EARDIS)

Centre Hospitalier Universitaire de Nīmes

Status: Enrolling

Conditions: Neoplasm Metastasis; Colorectal Cancer; Disseminated Cancer

Treatments: Other: Blood test

Study type: Observational

Funder types: Other

Identifiers

NCT05648240

NIMAO/2022-1/JFB01

Details and patient eligibility

About

The study authors hypothesize that in patients with intestinal polyps, tumor cells could disseminate and circulating factors could be secreted by the polyp. These two parameters could become biomarkers to refine the follow-up of patients and to establish targeted therapeutic strategies.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient to be examined by colonoscopy
• The patient must be a member or beneficiary of a health insurance plan

Exclusion criteria

• The subject is participating in a category 1 interventional study, or is in a period of exclusion determined by a previous study
• The subject signals their opposition to participate in the study
• It is impossible to give the subject informed information
• The patient is under safeguard of justice or state guardianship
• Patient pregnant or breastfeeding
• History of proven cancerous disease
• Patient followed for a chronic inflammatory bowel disease

Trial design

120 participants in 2 patient groups

Patients with polyps

Treatment:

Other: Blood test

Patients without polyps

Treatment:

Other: Blood test