Propensity Score Matched Comparison of HMP vs. SCS in Kidney Transplantation

Medical University Innsbruck

Status: Completed

Conditions: Delayed Graft Function

Study type: Observational

Funder types: Other

Identifiers

NCT04359173

HMP_SCS

Details and patient eligibility

About

Hypothermic machine perfusion (HMP) is considered superior to static cold storage (SCS) in kidney transplantation, but the true benefit in the real-world experience remains incompletely understood.

The aim of our study is to investigate the real-world impact of HMP on kidney graft function after deceased donor kidney transplant in an HMP cohort propensity score matched with SCS.

Propensity score matching will be based on CIT, ECD, gender mismatch, CMV mismatch, re-TX and ET-senior program with a caliper of 0.05

Enrollment: 347 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• single kidney transplantation from a deceased donor at Medical University of Innsbruck between 08/2015 and 12/2019

Exclusion criteria

• combined kidney transplantation with an other organ
• living donor kidney transplantation

Trial design

347 participants in 2 patient groups

Hypothermic machine perfusion (HMP)

Description:

patients who underwent kidney transplantation following HMP

Static cold storage (SCS)

Description:

patients who underwent kidney transplantation following SCS