Prophylactic Antibiotic Treatment for Hand Lacerations Involving Flexor and/or Extensor Tendon

HaEmek Medical Center, Israel

Status and phase: Completed; Phase 4

Conditions: Hand Laceration; Clean Laceration; Tendon Involved; No Bone Involved

Treatments: Drug: Antibiotic-Cefamezin

Study type: Interventional

Funder types: Other

Identifiers

NCT01899781

EMC-003812-CTIL

Details and patient eligibility

About

The investigators assume that simple hand lacerations involving flexors or extensors tendons, do not require prophylactic antibiotic treatment to prevent wound infection.

Full description

Hand lacerations are divided to "complicated" which involves tendons, nerves, bones, and joints, and "simple" which involves only cutaneous and subcutaneous tissue.

prophylactic antibiotic should not be given in a clean simple lacerations, and should be given when a bone is involve (open fracture). But there is not enough data, weather prophylactic antibiotic treatment should be given when only tendons are involved. The investigators will examine 2 groups of 30 patients each with clean hand lacerations involving tendons. One group will be treated with prophylactic antibiotic and the other wont be treated, randomly. The investigators assume that the rate of wound infection wont be different between the 2 groups.

Enrollment: 24 patients

Sex: All

Ages: 13 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Hand laceration
• Tendon involeved
• Clean laceration
• No bone involved

Exclusion criteria

• Pregnant
• Children
• Immunocompremised patients
• "Dirty" lacerations

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

24 participants in 1 patient group

with antibiotic and without antibiotic

Experimental group

Treatment:

Drug: Antibiotic-Cefamezin