Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty

Mayo Clinic

Status: Active, not recruiting

Conditions: Knee Pain Chronic

Treatments: Procedure: Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty

Study type: Interventional

Funder types: Other

Identifiers

NCT04028947

19-000527

Details and patient eligibility

About

Researchers are trying to determine if knee pain can be reduced by proactively protecting the free end of the saphenous nerve versus leaving it in the standard position during total knee arthroplasty.

Full description

Subjects scheduled for total knee arthroplasty will be randomized to two arms. One arm will have the standard saphenous nerve neurectomy during their surgery. The other arm will have the same neurectomy procedure with the free end of the nerve tucked into soft tissue to protect the nerve ending.

Enrollment: 178 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primary unilateral total knee arthroplasty candidate

Exclusion criteria

• Body Mass Index (BMI) >40
• Inflammatory arthritis
• Unable to follow up visits (long distance from Mayo Clinic)
• Poor compliance risk
• Health condition deemed by physician to preclude patient's ability to participate in the trial

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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178 participants in 2 patient groups

Standard TKA

No Intervention group

Description:

Subjects will have the standard procedure.

TKA with Neurectomy

Active Comparator group

Description:

Subjects will the nerve excised and protected with soft tissue.

Treatment:

Procedure: Prophylactic Infrapatellar Saphenous Neurectomy in Primary Total Knee Arthroplasty