Prophylactic Selective Lateral Neck Dissection in Patients With Papillary Thyroid Carcinoma

Pusan National University

Status: Completed

Conditions: Lymphatic Metastasis; Thyroid Neoplasm

Treatments: Procedure: prophylactic selective lateral neck dissection

Study type: Interventional

Funder types: Other

Identifiers

NCT01103557

PTC_CND_LND

Details and patient eligibility

About

The purpose of this study is to prospectively analyze the incidence of occult lateral neck metastasis (LNM) and to elucidate the factors that predict LNM in papillary thyroid carcinoma (PTC) with central neck metastasis (CNM) by performing prophylactic selective lateral neck dissection (SND).

Full description

The lymphatic drainage pattern of the thyroid is uniform and consistent, and therefore, metastatic patterns are relatively predictable. Initial nodal metastasis in PTC usually occurs in the paratracheal and pretracheal nodes in level VI of the central compartment of the ipsilateral neck and spreads to the lateral cervical lymph nodes. Macroscopic skip metastases to the lateral compartment of the neck in the absence of central disease are uncommon.

Enrollment: 62 patients

Sex: All

Ages: 20 to 76 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Papillary thyroid carcinoma with central neck metastasis
• No evidence of lateral neck metastasis as determined by high-resolution neck ultrasonography and computed tomography

Exclusion criteria

• History of previous thyroid operation
• Isthmic thyroid lesion

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)