Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy

Medical University of Vienna

Status: Completed

Conditions: Pneumonia, Ventilator-Associated

Treatments: Procedure: Continuous lateral rotation therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT00529776

EK 38/2004

Details and patient eligibility

About

Hypothesis: Ventilator associated pneumonia (VAP) in critically ill patients may be prevented by continuous lateral rotation therapy (CLRT) using specially designed, motor driven beds.

Patients are randomized to CLRT or supine position if mechanically ventilated and not suffering from pneumonia or ARDS within 48 hours after intubation. Prophylaxis of VAP is standardized in both groups. Primary endpoint is incidence of VAP, secondary endpoints are length of ventilation, length of stay and mortality.

Enrollment: 150 patients

Sex: All

Ages: 18 to 89 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Mechanically ventilated
• Intubated not longer than 48 h
• Medical cause for ICU admission
• Expected to be ventilated for > 48 hours

Exclusion criteria

• Pneumonia or ARDS present
• Postoperative patient

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

150 participants in 2 patient groups

1

Active Comparator group

Description:

Continuous lateral rotation therapy

Treatment:

Procedure: Continuous lateral rotation therapy

2

No Intervention group

Description:

Standard manual positioning (Supine position)