Propofol and Sevoflurane for Catheter-Related Bladder Discomfort

Seoul National University

Status: Completed

Conditions: Catheter Site Discomfort; Urinary Bladder Neoplasms; Complications; Anesthesia

Treatments: Drug: Sevoflurane; Drug: Propofol

Study type: Interventional

Funder types: Other

Identifiers

NCT02252445

CRBDPPFSEVO

Details and patient eligibility

About

The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.

Full description

The mechanism of catheter-related bladder discomfort is thought to be related to the muscarinic receptor. Propofol and desflurane are most widely used as an anesthetic agent. Propofol and desflurane are known to block the muscarinic receptor in different ways.

The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.

Enrollment: 82 patients

Sex: All

Ages: 19 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients scheduled for transurethral bladder excision under general anesthesia
• ASA I-III

Exclusion criteria

• Foley catheter less than 18 Fr.
• Patients with obstruction of urinary tract
• Patients with neurogenic bladder
• Patients with severe obesity
• Patients with neurologic disorder
• Patients with chronic pain
• Patients with allergic history to propofol or sevoflurane

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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82 participants in 2 patient groups

Propofol

Active Comparator group

Description:

Propofol will be administered as the anesthetic maintenance agent.

Treatment:

Drug: Propofol

Sevoflurane

Experimental group

Description:

Sevoflurane will be administered as the anesthetic maintenance agent.

Treatment:

Drug: Sevoflurane