Propofol Versus Dexmedetomidine for Prevention of Sevoflurane Agitation in Recipients of Living Donor Liver Transplantation

AlRefaey Kandeel

Status: Unknown

Conditions: Liver Transplantation

Treatments: Drug: dexmedetomedine; Drug: Propofol

Study type: Interventional

Funder types: Other

Identifiers

NCT02544906

LTx 7

Details and patient eligibility

About

The use of propofol or dexmedetomedine for prevention of sevofurane emergence agitation in LDLT recipients

Enrollment: 120 estimated patients

Sex: All

Ages: 30 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All recipients of living donor liver transplantation

Exclusion criteria

• patient refusal Allergy to either propofol or dexmedetomediene CNS disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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120 participants in 3 patient groups

Control

No Intervention group

Description:

No drugs will be given. the emergence agitation will be monitored and recorded

Propofol group

Experimental group

Description:

Propofol at dose of 1 mg/kg over 5 minutes will be started before extubation. the emergence agitation will be monitored and recorded

Treatment:

Drug: Propofol

dexmedetomedine group

Experimental group

Description:

dexmedetomedine at dose of .5 mic/kg over 5 minutes will be started before extubation. the emergence agitation will be monitored and recorded

Treatment:

Drug: dexmedetomedine