Propolis in Primary Herpetic Gingivostomatitis (RCT)

Fayoum University

Status: Completed

Conditions: Herpetic Gingivostomatitis

Treatments: Other: Placebo gel; Dietary Supplement: 5% propolis gel

Study type: Interventional

Funder types: Other

Identifiers

NCT06778655

1212025

Details and patient eligibility

About

The purpose of the present study is to investigate the efficacy of 5% propolis gel in the treatment of primary herpetic gingivostomatitis in children and its effect on salivary IFN-γ levels.

Enrollment: 60 patients

Sex: All

Ages: 3 to 8 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical manifestations suggestive of PHGS
• positive culture for HSV-1

Exclusion criteria

• negative culture for HSV-1
• allergic to honey or its products
• patients diagnosed with any systemic diseases, immunosuppressed or immunocompromised patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Propolis group

Experimental group

Treatment:

Dietary Supplement: 5% propolis gel

Control group

Placebo Comparator group

Treatment:

Other: Placebo gel