Propolis In The Treatment Of Periodontitis (PROPOLIS)

Rajarajeswari Dental College & Hospital

Status: Unknown

Conditions: Chronic Periodontitis

Treatments: Procedure: scaling root planing; Drug: Propolis

Study type: Interventional

Funder types: Other

Identifiers

NCT01943877

971987

Details and patient eligibility

About

This study was conducted to evaluate by clinical and microbiological parameters the effect of locally delivered propolis as an adjunct to scaling and root planing in the treatment of chronic periodontitis.

Full description

Materials and Methods: 20 subjects diagnosed with chronic periodontitis were recruited to participate in split-mouth design and provided informed consent. Subgingival plaque sampling and clinical recording at baseline, 15 days and 1 month was performed. The patients received scaling and root planing, followed by Propolis administration subgingivally in the test sites. Significant differences between test and control were evaluated using the Mann-Whitney U test and Wilcoxon rank test.

Enrollment: 20 patients

Sex: All

Ages: 25 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• good general health
• chronic periodontitis
• minimum of 20 natural teeth with at least one pocket per quadrant
• probing depth (PD) between 5 and 8 mm.

Exclusion criteria

• subgingival instrumentation within 3 months
• antibiotic therapy within 3 months prior to the start of the study;
• smokers
• pregnant or nursing women
• intolerance or allergy to honey products

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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20 participants in 2 patient groups

Propolis

Experimental group

Treatment:

Procedure: scaling root planing

Drug: Propolis

scaling and root planing

Sham Comparator group

Treatment:

Procedure: scaling root planing