Propositive (Protecting Positive People From Meningococcal Infection) Follow-up Study

St George's, University of London

Status: Unknown

Conditions: Meningococcal Disease; HIV/AIDS

Treatments: Diagnostic Test: Serum Bactericidal Assays

Study type: Observational

Funder types: Other

Identifiers

NCT04239430

2019.0374

Details and patient eligibility

About

The need for and timing of booster doses of meningococcal vaccines in People Living with HIV (PLWHIV) is currently unknown. As such it is impossible for clinicians to recommend booster doses or to know if and when these might be necessary.We propose to follow up a group of participants from the Propositive study who received two doses of both MenB (Bexsero) and MenACWY (Menveo). This was a group of PLWHIV between the ages 18-45 years. We propose following up these participants at 18 and 30 months post completion of two doses of vaccine and investigating their immunological response.

Enrollment: 55 estimated patients

Sex: All

Ages: 18 to 47 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Received vaccination with Bexsero and Menveo during Propositive study
• Able to sign fully informed consent
• Able to comply with study requirements

Exclusion criteria

• Unwilling or unable to comply with study requirements