Prospective Collection of Surplus Surgical Tumor Tissues and Pre-surgical Blood Samples (GBCPRT0008)


Global BioClinical




Breast Cancer
Hematologic Cancer
Lung Cancer
Prostate Cancer
Colorectal Cancer

Study type


Funder types




Details and patient eligibility


The study is intended to collect specimens to support the application of genome analysis technologies, including large-scale genome sequencing. This study will ultimately provide cancer researchers with specimens that they can use to develop comprehensive catalogs of genomic information on at least 50 types of human cancer. The study will create a resource available to the worldwide research community that could be used to identify and accelerate the development of new diagnostic and prognostic markers, new targets for pharmaceutical interventions, and new cancer prevention and treatment strategies. This study will be a competitive enrollment study conducted at multiple institutions.

Full description

This study will enroll subjects diagnosed with various cancers and who are scheduled to undergo surgical treatment. Prior to scheduled surgery, subjects will be asked to donate a 10-20 ml blood sample. After surgery, surplus tissues (including tumor and adjacent normal tissues) not required for diagnosis will be collected. Subject clinical information will be collected, including basic demographic information, medical history, family history, current cancer history and treatment. After surgery, a final pathology report will be obtained for each subject's surgical specimen. In some instances and based on the cancer indications required, longitudinal data may also be collected at a frequency of every 6 months to once per year. Longitudinal data will include information on study subject survival and disease recurrence.




18 to 90 years old


No Healthy Volunteers

Inclusion criteria

  • Any adult age
  • Any sex
  • Able to provide consent for surplus tissue and/or blood donation
  • Diagnosed with one of the cancer indications listed below:
  • Scheduled to undergo surgical resection of tumor (exception for hematological cancers)
  • Have not yet received treatment for cancer

Exclusion criteria

  • Not diagnosed with required cancer indication
  • Not scheduled to undergo surgical resection of the tumor
  • Have already received cancer treatment (such as chemotherapy, radiation, surgery) for the current cancer or a previously diagnosed cancer
  • Not able to donate an adequate volume of blood to meet minimum requirements


  1. Bladder Cancer - Urothelial carcinoma - nonpapillary
  2. Bladder Cancer - Urothelial carcinoma - papillary
  3. Brain Cancer - Astrocytoma
  4. Brain Cancer - Glioblastoma
  5. Brain Cancer - Medulloblastoma
  6. Breast Cancer - Ductal Carcinoma
  7. Breast Cancer - Lobular Carcinoma
  8. Cervical Cancer - Squamous Cell Carcinoma
  9. Colorectal Cancer - Adenocarcinoma
  10. Esophageal Cancer - Adenocarcinoma
  11. Gastric Cancer
  12. Head and Neck Cancer - Squamous Cell Carcinoma
  13. Hematologic Cancer - Acute Lymphocytic Leukemia (ALL)
  14. Hematologic Cancer - Acute Myeloid Leukemia (AML)
  15. Hematologic Cancer - Chronic Lymphocytic Leukemia (CLL)
  16. Hematologic Cancer - Diffuse Large B-cell Lymphoma
  17. Hematologic Cancer - Multiple Myeloma (MM)
  18. Hematologic Cancer - Non-Hodgkins Lymphoma (NHL)
  19. Kidney Cancer - Papillary Carcinoma
  20. Kidney Cancer - Renal cell Carcinoma
  21. Liver Cancer - Hepatocellular Carcinoma
  22. Lung Cancer - Adenocarcinoma
  23. Lung Cancer - Squamous Cell Cancer
  24. Melanoma
  25. Pancreatic Cancer - Ductal Adenocarcinoma
  26. Prostate Cancer - Adenocarcinoma
  27. Sarcomas
  28. Thyroid Cancer - Follicular Carcinoma
  29. Thyroid Cancer - Papillary Carcinoma
  30. Uterine Cancer - Endometrial Carcinoma

Trial design

0 participants in 1 patient group

Cancer Subjects

Trial contacts and locations



Data sourced from

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