Prospective Evaluation of Electrical Cardiometry for Hemodynamic Monitoring in COPD Patients Admitted to the Respiratory Intensive Care Unit

Assiut University

Status: Not yet enrolling

Conditions: Non-invasive Electrical Cardiometry

Study type: Observational

Funder types: Other

Identifiers

NCT07208578

Non-invasive Hemodynamic

Details and patient eligibility

About

This study investigates the reliability and clinical usefulness of non-invasive electrical cardiometry (ICON® device) in monitoring hemodynamic changes in COPD patients admitted to the respiratory intensive care unit (RICU).

Full description

hemodynamic monitoring is critical in critically ill patients, especially those with COPD experiencing acute respiratory failure. Traditional invasive methods such as pulmonary artery catheterization are accurate but carry procedural risks. The ICON® device enables real-time, continuous, non-invasive assessment of parameters like cardiac output, stroke volume, systemic vascular resistance, and thoracic fluid content using thoracic bioimpedance. This prospective observational study will assess its reliability against clinical outcomes and evaluate the influence of different ventilation strategies (invasive, non-invasive, no ventilation) on hemodynamic changes. Data will be collected serially throughout ICU stay to determine ICON's contribution to optimizing patient management and risk stratification.

Enrollment: 96 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years

Admission to RICU with COPD or COPD-related acute respiratory failure

Informed consent provided by patient or legal representative

Exclusion criteria

• patients <18 years

Pregnant women

Injuries, burns, or skin conditions preventing electrode placement

Patients with uncontrolled seizures

Patients needing electrical DC shock

Refusal or withdrawal of informed consent

Trial design

96 participants in 3 patient groups

Invasive Mechanical Ventilation Arm

Description:

COPD patients requiring intubation and invasive ventilation support. Hemodynamics will be continuously monitored using ICON to evaluate changes under invasive ventilation physiology.

Non Invasive Mechanical Ventilation Arm

Description:

COPD patients managed with NIV (e.g., BiPAP/CPAP). The arm will assess ICON's ability to track hemodynamic responses to positive pressure without intubation.

No Mechanical Ventilation Arm

Description:

COPD patients receiving supplemental oxygen therapy or room air only. This group serves as a baseline to study hemodynamic changes without ventilatory support.