Prospective Evaluation of Radiotherapy Using Magnetic Resonance Image Guided Treatment (PERMIT)

I

Institute of Cancer Research, United Kingdom

Status

Enrolling

Conditions

Cancer

Treatments

Device: MR Linac

Study type

Interventional

Funder types

Other

Identifiers

NCT03727698
CCR4841

Details and patient eligibility

About

The purpose of PERMIT is to collect information on the treatment of radiotherapy patients using a new radiotherapy machine that includes magnetic Resonance (MR) imaging (MR linac) to guide treatment. The aim is to use this information to support the introduction of MR Linac into clinical practice. PERMIT will collect details on patients treated on the MR linac plus details on their side effects and other outcomes. This information plus technical and imaging information will be combined with information from other centres using this machine. By doing so this will help us learn how best to use the MR Linac in the future and design new radiotherapy protocols

Enrollment

200 estimated patients

Sex

All

Ages

5+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Radiotherapy treatment suitable to be delivered on the MR Linac.
  • Patient provides written, informed consent and/or authorization.
  • Patients between the ages of 5 and under 16 years old may enter protocol with parental/guardian consent.

Exclusion criteria

  • Contra-indications to MR imaging.
  • Radiotherapy not suitable for delivery on the MR Linac e.g. those with extended field lengths (exceeding 20 cm).

Trial design

200 participants in 1 patient group

Radiotherapy delivered on the MR Linac
Experimental group
Description:
MR Guided radiotherapy treatment
Treatment:
Device: MR Linac

Trial contacts and locations

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Central trial contact

Robert Huddart; Lorna Bower, BSc

Data sourced from clinicaltrials.gov

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