Prospective Evaluation of the Relation Between Different Questionnaires Measuring Radiation-induced Side-effect

M.D. Anderson Cancer Center

Status: Enrolling

Conditions: Radiation

Treatments: Other: EORTC HN35; Other: EORTC QLQ-C30; Other: MDASI-HN

Study type: Observational

Funder types: Other

Identifiers

NCT06295783

2023-1059

NCI-2024-01955 (Other Identifier)

Details and patient eligibility

About

To learn more about how you would rate the intensity or severity of your symptoms during or after radiation therapy using questionnaires with different rating scales.

Full description

Primary Objectives:

• To investigate how different toxicity questionnaires with different scoring systems can be reliably translated to each other by estimating different measures of correlation between items and summary scores across different questionnaires.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• English as a primary language
• Participants with a diagnosis of HNC undergoing active curative RT or having received curative RT within the past 5 years at MD Anderson
• Ability to complete the survey(s) of their own volition

Exclusion criteria

• Age < 18 years
• Non-English speaking participants
• Participants who are receiving or have received RT in a non-HN site.
• Participants in follow up and over 5 years from post-treatment
• Neurocognitive deficits that render patients unable to complete the survey(s) on their own.

Trial design

300 participants in 1 patient group

Head and Neck Cancer (HNC) Questionnaire

Description:

Participants will be asked to fill out three head and neck cancer (HNC) questionnaires during your visits to the clinic: 1. The MDASI-HN questionnaire (standard-of-care) has 28 questions. 2. The EORTC QLQ-HN35 questionnaire has 35 questions. 3. The EORTC QLQ-30 questionnaire has 30 questions.

Treatment:

Other: MDASI-HN

Other: EORTC HN35

Other: EORTC QLQ-C30