Prospective Memory in Parkinson's Disease (ProMem)

The Washington University

Status: Completed

Conditions: Prospective Memory; Parkinson's Disease; Memory

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00913640

05-0203

Details and patient eligibility

About

The investigators tested whether prospective memory is impaired in individuals with Parkinson's Disease compared to controls using reliable and validated experimental measures. Also, the investigators assessed the impact of Parkinson's medication on prospective memory performance in PD to better estimate prospective memory function in PD patients' everyday (chronically treated) life.

Enrollment: 52 patients

Sex: All

Ages: 40 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• PD Group:

  • Clinically definite PD
  • 40-70 years old
  • Hoehn and Yahr stage I,II,III
  • Currently treated with Levodopa/carbidopa

• Control Group:

  • 40-70 years old
  • Spouses of PD Group preferred

Exclusion criteria

• PD Group and Control Group:

  • Significant neurological problems
  • Significant current psychiatric diagnoses
  • Mini Mental Status Exam score < 24 (MMSE)
  • Any significant abnormality on brain imaging
  • MPTP exposure
  • Control Participants met the same exclusion criteria described above as well as a biological family history of PD

Trial design

52 participants in 2 patient groups

PD Group

Control Group