Cardiovascular and Prothrombotic Risk in Patients With Oral Lichen Planus. (LPO_RCP)

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Not yet enrolling

Conditions: Oral Lichen Planus

Treatments: Other: blood sample collection

Study type: Observational

Funder types: Other

Identifiers

NCT07151014

7635

Details and patient eligibility

About

The primary objective is to evaluate the cardiovascular profile and the risk of thrombotic events in patients affected by Oral Lichen Planus.

Full description

Evaluation of thrombophilia screening parameters, antiphospholipid antibody levels, and platelet aggregability in a cohort of patients affected by Oral Lichen Planus.

Enrollment: 55 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with a clinical and histological diagnosis of Oral Lichen Planus
• Age > 18 years
• Patients who agree to sign the informed consent form

Exclusion criteria

• Patients under 18 years of age
• Patients who do not agree to sign the informed consent form
• Patients without a diagnosis of Oral Lichen Planus
• Patients with previously known cardiac diseases
• History of major cardiovascular events (myocardial infarction, ischemic stroke, TIA)
• Patients with overt heart failure (NYHA class III-IV)
• Cardiomyopathies not related to the studied risk factors (e.g., genetic hypertrophic cardiomyopathy)
• Patients undergoing anticoagulant therapy
• Patients with primary or secondary conditions associated with increased cardiovascular risk

Trial design