Prospective Observational Analysis of Circulating Endocan Levels in Patients Presenting With Acute Diverticulitis (DIVENDO)

IRCCS Ospedale San Raffaele

Status: Not yet enrolling

Conditions: Diverticulitis

Study type: Observational

Funder types: Other

Identifiers

NCT07027007

DIVENDO STUDY

Details and patient eligibility

About

Quantify the level of endocan in blood samples collected from patients with acute diverticulitis in the emergency department. Determine if endocan levels are correlated with the severity of diverticulitis according to the WSES classification. Assess whether patients requiring emergency surgical intervention have higher endocan values compared to others.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who have signed informed consent
• Patients who are affected by acute diverticulitis after clinical evaluation and imaging (i.e. u.s. or CeCT)

Exclusion criteria

• Immunosuppressed patients
• Patients suffering chronic inflammatory diseases
• Patients with concomitant malignancy, cardiac, renal and haepatic failure
• History of major vascular surgery (aneurysmectomy)
• Pregnant women
• Patients participating in other studies that may interfere with the outcome of the intervention.

Trial design

60 participants in 1 patient group

patients with acute diverticulitis

Description:

Patients admitted to the emergency department with acute diverticulitis classified according to WSES statements.