Prospective Observational Correlation of Sperm Assay Results With Blastocyst Formation

Bruce Shapiro M.D.

Status: Completed

Conditions: Infertility

Treatments: Other: SpermComet assay

Study type: Observational

Funder types: Industry

Identifiers

NCT02031549

SAIRB-13-0038

Details and patient eligibility

About

We will investigate potential correlation between SpermComet DNA fragmentation assay results and IVF cycle outcome.

Full description

A "SpermComet" assay will be used to characterize DNA fragmentation of surplus sperm samples remaining after in vitro fertilization (IVF) cycles. We will investigate potential correlation between these assay results and the outcomes of IVF cycles that used those sperm samples.

Enrollment: 40 patients

Sex: Male

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Undergoing IVF
• Surplus sperm available after oocyte insemination
• Consented

Exclusion criteria

• Surgical sperm extraction
• Use of donated sperm or oocytes
• No minors may participate

Trial design

40 participants in 1 patient group

SpermComet Assay

Description:

All study subjects will have their surplus sperm analyzed for DNA fragmentation with the SpermComet assay.

Treatment:

Other: SpermComet assay