Prospective Observational Study to Compare REMS vs NEWS2 for Patients Presenting to the ED With Sepsis

Jubilee Mission Medical College and Research Institute

Status: Completed

Conditions: Sepsis

Treatments: Drug: Antibiotics, Vasopressors

Study type: Observational

Funder types: Other

Identifiers

NCT07171918

38/22/IEC/JMMC&RI

Details and patient eligibility

About

Prospective observational study to determine the utility of Rapid Emergency Medicine Score (REMS) in comparison to National Early Warning Score2 (NEWS2) for predicting morbidity and mortality among patients presenting to the Emergency Department with clinical suspicion of Sepsis

Full description

Rapid Emergency Medicine Score (REMS) is an attenuated version of the Acute Physiology and Chronic Health Evaluation (APACHE) II score and has utility in predicting mortality in non- surgical patients. The NEWS2 can be used on all hospitalized patients to allow for the early detection of clinical deterioration and potential need for higher level of care. NEWS2 is closely associated with sepsis, however REMS is not so. But in recent studies comparing other EWS (Early Warning Scores) of sepsis, REMS was found to be superior.

Hence comparing REMs against NEWS2 to determine prognostication value of both scores in sepsis.

Enrollment: 130 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients presenting to ED of Tertiary Care Hospital in Thrissur.
• Patients age >/=18 years
• Patients who give informed consent for participation in the study.
• Suspicion of sepsis at the time of presentation to ED as per SSC Guidelines 2021

Exclusion criteria

• All patients with an alternate diagnosis other than sepsis at the time of discharge.
• Patients referred from other hospitals with diagnosis of sepsis, after initiation of treatment

Trial design

130 participants in 1 patient group

Sepsis patients

Treatment:

Drug: Antibiotics, Vasopressors