Prospective Pakistan Registry of Echocardiographic Screening in Asymptomatic Pregnant Women (PRESAP)

National Institute of Cardiovascular Diseases, Pakistan

Status: Enrolling

Conditions: Cardiovascular Diseases in Pregnancy

Study type: Observational

Funder types: Other

Identifiers

NCT06004544

IRB-33/2023

Details and patient eligibility

About

Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed. Ejection fraction (EF) was quantified using biplane Simpson's method.

Full description

Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed, including parasternal long and short, apical 4- and 2-chamber views. Continuous wave and pulse wave Doppler were used to assess left ventricular outflow tract (LVOT) gradients. Left ventricular (LV) function was quantified using biplane Simpson's method and visually assessed by two independent readers. Patients with significant valve disease or congenital heart disease underwent complete TTE. Those diagnosed with LV dysfunction or other cardiovascular diseases (CVD) were referred to the Cardio-Obstetrics clinic for further management and long-term follow-up.

Enrollment: 10,000 estimated patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Obstetric patients attending routine antenatal visits

Exclusion criteria

• Patients refused to give consent for echocardiography or participation in the study