Prospective Randomized Comparison of Zymar(Gatifloxacin) and Vigamox (Moxifloxacin) in Killing Conjunctival Bacterial Flora Following a One-hour Application

Stanford University

Status: Withdrawn

Conditions: Conjunctical Flora

Treatments: Drug: gatifloxacin, moxifloxacin

Study type: Interventional

Funder types: Other

Identifiers

NCT00466570

8924

Details and patient eligibility

About

Topical ophthalmic antibiotics are common prescribed just prior to eye surgery to lower the risk of infection. Previous studies have suggested that antibiotics containing a preservative (Zymar) kill bacteria much quicker than those without a preservative (Vigamox). The purpose of this research is to compare how quickly to the two commonly prescribed antibiotics eliminate bacteria from the eye surface.

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age- older than 50 years of age
• Diagnosis- Cataract or had cataract surgery

Exclusion criteria

• Systemic or topical antibiotic treatment within 30 days
• Use of systemic or topical steroids
• Active ocular infection
• Ocular surgery in the past 6 months
• Allergy to fluoroquinolones

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Single Blind