Prospective Regional Epilepsy Database (PREDICT)

Sahlgrenska University Hospital

Status: Enrolling

Conditions: Epilepsy

Treatments: Other: Health care; Diagnostic Test: Tests; Other: Demographics and psychosocial; Other: Epilepsy; Other: Seizure status

Study type: Observational

Funder types: Other

Identifiers

NCT04559919

2020-00853

Details and patient eligibility

About

PREDICT is an observational study following adults with an unprovoked seizure or epilepsy in the health care region of western Sweden. The objective is to identify biomarkers and/or genetic predisposition of relevance for diagnosis and/or treatment of epilepsy and study the long-term prognosis and consequences of epilepsy.

Full description

Adults over 18 years of age, with an unprovoked seizure in the last year or epilepsy, resident in the health care region of western Sweden (VGR) at the time of inclusion.

Baseline data and outcome variables are collected from several patient registries: the electronic medical records system in the health care region VGR and Swedish National Registers of healthcare, income, and employment managed by The National Board of Health and Welfare or Statistics Sweden, both of which are government agencies.

Enrollment: 1,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Over 18 years of age
• An unprovoked seizure within the last year or a diagnosis of epilepsy according to the current International League Against Epilepsy definition (epilepsy with seizure in the last ten or antiepileptic drug treatment in the last five years)

Exclusion criteria

• Expected survival less than two years
• Inability to give informed consent

Trial design

1,000 participants in 1 patient group

Adults with epilepsy

Description:

Adults over 18 years of age, with an unprovoked seizure in the last year or epilepsy, resident in VGR at the time of inclusion. Languages available: Swedish, English, Arabic. Based on the clinical information, patients can be categorized into relevant groups; single seizure, seizure-free with epilepsy, and drug-resistant epilepsy. Subgroups may also be selected based on age, sex, epilepsy sub-diagnosis, cause of epilepsy, use of a particular antiepileptic drug, or experience of a particular side effect.

Treatment:

Other: Seizure status

Other: Demographics and psychosocial

Other: Epilepsy

Diagnostic Test: Tests

Other: Health care