Prospective Registry of Patients With Pancreas Adenocarcinoma Resectable and Borderline (PaNLoCat)

Hospital del Mar

Status: Completed

Conditions: Chemotherapy Effect; Pancreas Cancer

Treatments: Procedure: Neoadyuvant therapy

Study type: Observational

Funder types: Other

Identifiers

NCT05514171

PaNLoCat_v4

Details and patient eligibility

About

Unlike other types of gastrointestinal tumors, there is controversial evidence of the efficacy of neoadjuvant therapy in patients with borderline and resectable adenocarcinoma (ADK) of the pancreas, the objective of this study is to perform a "snapshot" of the usual practice in our setting in terms of neoadjuvant therapy in ADK, both in terms of the different regimens used as well as the results in terms of morbidity, mortality and survival.

Likewise, in a second phase, a prospective registry of patients included in the neoadjuvant regimen for both resectable and borderline ADK diagnosed in Catalonia will be launched, which will provide us with valuable information to try to answer open questions in the context of borderline and resectable ADK treatment.

Enrollment: 300 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• resectable or borderline pancreas ADK
• with or without radiotherapy
• any type of approach
• any type of surgery

Exclusion criteria

• locally advanced ADK
• No consent

Trial design

300 participants in 2 patient groups

Neoadyuvant therapy

Description:

Patients with borderline or resectable ADK subjected to neoadyuvant therapy

Treatment:

Procedure: Neoadyuvant therapy

Upfront surgery

Description:

Patients with borderline or resectable ADK who undergo upfront surgery