Prospective Study for Prognostic Biomarkers of Nasopharyngeal Carcinoma
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About
The purpose of this clinical research project is to explore potential biomarkers and validate the predictive and prognostic value of molecular signature in nasopharyngeal carcinoma.
Full description
Objectives:
Primary: Evaluation of failure-free survival after three years of patients of nasopharyngeal carcinoma.
Secondary: Evaluation of overall survival after three years of patients of nasopharyngeal carcinoma.
Outline: This is a multicenter observational study. Tumor tissue specimens are obtained from the Sun Yat-sen University Cancer Center and Affiliated Hospital of Guilin Medical University. The samples are analyzed for biomarkers. The biomarkers are correlated with clinical outcomes (failure-free survival, overall survival, tumor response to treatment, distant metastasis, recurrence and death).
The aim of the analysis is to explore potential biomarkers and validate the predictive and prognostic value of molecular signature in nasopharyngeal carcinoma. This will lead to the definition of risk groups and stratification of patients and will help to precision medicine of nasopharyngeal carcinoma.
Enrollment
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Volunteers
Inclusion criteria
- Patients with newly histologically confirmed nasopharyngeal carcinoma
- No evidence of distant metastasis (M0)
- Written informed consent
Exclusion criteria
- Treatment with palliative intent
Trial contacts and locations
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Central trial contact
Jun Ma, M.D.
Data sourced from clinicaltrials.gov
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