Prospective Study on the Incidence of Adrenal Crisis in Patients With Chronic Adrenal Insufficiency

University of Wuerzburg

Status: Completed

Conditions: Adrenal Insufficiency

Study type: Observational

Funder types: Other

Identifiers

NCT01184209

WueAC17/07

Details and patient eligibility

About

Prospective study to evaluate incidence, causes and potential risk factors for adrenal crisis in patients with chronic adrenal insufficiency.

Full description

This is a prospective study following patients with chronic adrenal insufficiency by contacting them every 6 months via questionnaires and telephone. QUestionnaires assess incidence and causes of adrenal crisis, frequency of hospitalization.

Enrollment: 444 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• chronic primary or secondary adrenal insufficiency requiring glucocorticoid substitution therapy

Exclusion criteria

• adrenocortical carcinoma
• long term glucocorticoid treatment above 7.5 mg prednisone equivalent dose for other reasons than adrenal insufficiency
• age < 18 years