Prospective Surveillance For Respiratory Virus Infections In Children Undergoing Hematopoietic Stem Cell Transplantation

St. Jude Children's Research Hospital

Status: Completed

Conditions: Respiratory Virus Infections

Treatments: Other: Nasopharyngeal Washes; Other: Respiratory viral culture; Other: Fluorescent antibody detection

Study type: Observational

Funder types: Other

Identifiers

NCT00667303

BMTRV

Details and patient eligibility

About

The Study aims to prospectively survey the incidence of respiratory virus infections using molecular methodologies, in children undergoing hematopoietic stem cell transplantation

Full description

Samples will be collected with a nasopharyngeal wash and processed for direct fluorescent antibody, culture and Polymerase chain reaction (PCR)

Enrollment: 51 patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age: Birth to 18 years.
• Patients undergoing an allogeneic HSCT for any disease.
• Parent or guardian willing to sign informed consent.

Exclusion criteria

• Intra nasal lesion which precludes the performance of the nasopharyngeal wash.
• Patients on Continuous Positive Airway Pressure (CPAP) or Bilevel Positive Airway Pressure (BiPAP).

Trial design

51 participants in 1 patient group

1

Treatment:

Other: Fluorescent antibody detection

Other: Nasopharyngeal Washes

Other: Respiratory viral culture