Prostaglandin F2-alpha (PGF2α) in Vitiligo

Cairo University (CU)

Status: Unknown

Conditions: Vitiligo

Treatments: Other: Skin biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT03755830

Dermatology 10

Details and patient eligibility

About

study the cutaneous expression of PGF2α in vitiligo patients and compare it with normal control subjects.

Full description

Measurement of tissue levels of PGF2α in vitiligo patients and compare them with healthy controls.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with non-segmental vitiligo.
• Both sexes.
• Age < 18 years old.
• New cases or cases not receiving any medications for at least 3 months ago.

Exclusion criteria

• Age: Patients < 18 years.
• Segmental or universal vitiligo.
• Pregnant and lactating females.

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

vitiligo patients

Active Comparator group

Description:

Two skin biopsies (lesional and non-lesional) will be taken from every patient.

Treatment:

Other: Skin biopsy

healthy controls

Experimental group

Description:

A skin biopsy will be taken from each control subject.

Treatment:

Other: Skin biopsy