Prostaglandins Use Before Mirena IUD Insertion in Prev CS Women During Lactational Amenorrhea

Cairo University (CU)

Status: Unknown

Conditions: to Study the Estimate Difficulty of Insertion Mirena IUD With Use of Prostaglandins

Treatments: Drug: Misoprostol

Study type: Observational

Funder types: Other

Identifiers

NCT04646161

professor

Details and patient eligibility

About

This is a prospective randomized controlled study to determine the effect of prostaglandin intake before Mirena IUD insertion It was conducted at the Department of Obstetrics & Gynecology, Kasr El-Ainy Teaching Hospital, Faculty of Medicine, Cairo University,

Full description

The study aiming to measure the estimate difficulty of insertion of the Mirena IUD by using prostaglandins 2 hours before the procedure and the effect of prostaglandins to make this procedure easy with other side effects and complications as bleeding perforation, nausea, vomiting, failure of insertion and comparing them with a placebo group who didn't receive prostaglandins

Enrollment: 400 estimated patients

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1- Women in lactational amenoeehea with pregnancy test negative 2- Women who had caesarean section within 6 monthes of IUD insertion 3- No medical disorders

Exclusion criteria

• 1- Women in regular menses 2- Medical disorders 3- Nulligravida or muligravida with NVD 4- Women with history of Previous CS more than one CS 5- Any congenital uterine anomalies, fibroids and adenomysis 6- Chronic pelvic pain 7- Intrauterine adhesions 8- Spasmodic dysmenohrrea 9- Allergy to misoprostol

Trial design

400 participants in 2 patient groups

prostaglandins before iud insertion group

Description:

this group will receive 200 mcg prostaglandins in form of misoprostol 2 hrs before mirena iud insertion

Treatment:

Drug: Misoprostol

placebo group

Description:

this group will receive placebo tablet before mirena iud insertion